2014 Symposium
Session I 8:30 am – 9:15 am
Curriculum and Modules of Cardiovascular Translational Research
Moderators: Spencer King, Anthony DeMaria
8:30 am – 8:45 am ISCTR/ACC Mission and Curriculum in Cardiovascular Translational Research
Nabil Dib View Presentation
8:45 am – 9:00 am ISCTR/ACC Scholarship in Cardiovascular Translational Research
Spencer King View Presentation
9:00 am – 9:05 am ISCTR/ACC Scholar Recipient’s Experience
Chun Lin View Presentation
9:05 am – 9:20 am Components of Cardiovascular Translational Research Centers
Anthony DeMaria View Presentation
9:20 am – 9:35 am Panel Discussion: Spencer King, Anthony DeMaria
Nabil Dib View Presentation
Session II 9:40 am – 12:10 pm
CV Translational Research Pathway for Devices
Moderators: Magdi Yacoub, Blase Carabello
9:40 am – 10:10 am Regulatory Requirement for Cardiovascular Devices (510k, IDE and PMA)
Bram Zuckerman View Presentation
10:10 am – 10:20 am Translational Pathway for Catheter Development: 510(k) and CE Mark
Nabil Dib View Presentation
10:20 am – 10:35 am Translational Pathway for Percutaneous Aortic Valve Replacement
Alain Cribier View Presentation
10:35 am -10:50 am Translational Pathway for Percutaneous Mitral Valve Repair/Replacement
David Reuter View Presentation
10:50 am – 11:05 am Translational Pathway for Device Development for Heart Failure
Daniel Burkhoff View Presentation
11:05 am – 11:20 am Translational Pathway for Ventricular Assist Devices
Magdi Yacoub View Presentation
11:20 am – 11:35 am Investigational and New Cardiovascular Devices Strategy and Decision Making for Reimbursement
Jack Lewin View Presentation
11:35 am – 11:50 am How Can The Translational Research Pathway for Devices Bring First in Man Testing Back to the US?
Charles Simonton View Presentation
11:50 am – 12:10 pm Panel Discussion: Magdi Yacoub, Blase Carabello, Bram Zuckerman, Alain Cribier, David Reuter,
Daniel Burkhoff, Jack Lewin, Charles Simonton View Presentation
Lunch 12:10 pm – 1:00 pm
Session III 1:00 pm – 4:00 pm
Cardiovascular Translational Research Pathway for Biologics
Moderators: Stefanie Dimmeler and Daniel Burkhoff
1:00 pm – 1:15 pm Regulatory Requirement for Biologics, The IND Application
Steve Winitsky, FDA View Presentation
1:15 pm – 1:30 pm Cellular Product Development
Eduardo Marban View Presentation
1:30 pm – 1:45 pm Cell Tracking using MRI
Brooke Helfer View Presentation
1:45 pm – 2:00 pm Pathology Evaluation for Regenerative Therapy
Stefanie Dimmeler
2:00 pm – 2:15 pm Animal Model MI, CHF and Angina for Biologics Evaluation
Steven Chamuleau View Presentation
2:15 pm – 2:30 pm Panel Discussion: Stefanie Dimmeler, Steve Winitsky, Eduardo Marban, Brooke Helfer, and Steven
Chamuleau View Presentation
Break (15 minutes)
2:30 pm – 2:45 pm Methods of Delivery for Biologics
Nabil Dib View Presentation
2:45 pm – 3:00 pm Clinical Trial Design and Endpoints for Biologics: Phase I, II, & III For MI, CHF and Refractory
Angina
Andreas Zeiher
3:00 pm – 3:15 pm Pre-Clinical and Clinical Imaging for Biologics Outcome
Didier Locca View Presentation
3:15 pm – 3:30 pm Should Biological Disease Modification be Measured the Same Way as Daily Pharmacologic Therapy?
Doug Losordo View Presentation
3:30 pm – 3:45 pm How Do We Know if the Heart Gets Better? (Ejection Fraction)
Blase Carabello View Presentation
3:45 pm – 4:00 pm Panel Discussion: Andreas Zeiher, Nabil Dib, Didier Locca, Blase Carabello, Doug Losordo View Presentation
Session IV 4:00 pm – 5:15 pm
CV Translational Pathway for Drugs, Genomic and Personalized Medicine
Moderators: Didier Locca and Robert Roberts
4:00 pm – 4:15 pm Cardiovascular Translational Pathway for Drugs
Hendrik Tevaearai – View Presentation
4:15 pm – 4:30 pm Personalized Medicine
Robert Roberts View Presentation
4:30 pm – 4:45 pm Patient Specific Stem Cells and Cardiovascular Drug Discovery
Joseph Wu View Presentation
4:45 pm – 5:15 pm Panel Discussion: Robert Roberts, Joseph Wu, Hendrik Tevaearai View Presentation
Conclusion
