Translational Pathways for Cardiovascular Devices – Session II: The Endpoints for Transcatheter Aortic Valve Development Practice Quiz – ISCTR | International Society for Cardiovascular Translational Research

Which of the following combinations are clinical endpoints?

All of the following are clinical endpoints used in a TAVR clinical trial except?

Which of the following statements is correct regarding surrogate endpoints?

Surrogate endpoints are associated with the outcome but are not clinically relevant
Advantage of surrogate endpoints is that they can enable a higher number of events
Quality of life is not considered a surrogate
Imaging endpoints are not considered surrogates

Which of the following is correct regarding the Finkelstein-Schoenfeld Methodology?

Hierarchy is created for endpoints, such as mortality and quality of life
Each patient in Arm A is compared with each patient in Arm B and a win, loss, or tie is declared
This method increases power and reduces sample size compared to the simple composite endpoint method
All of the above