Practice Quiz: Large Animal Model for Heart Failure, Valvular Disease, Coronary Artery Disease, and Device Testing – Daniel Burkhoff – ISCTR | International Society for Cardiovascular Translational Research

Which one of the following is correct regarding preclinical animal testing?

Human diseases are easily mimicked in the animal model

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Human anatomy is different from animal anatomy

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Diseased vs. normal model does not affect the biological reaction

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Which of the following statements is incorrect?

Rat models are easier than mouse models to study remodeling

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Dog is not the preferable model for percutaneous devices evaluation because of the small body size

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Sheep have an increased mortality compared to pigs when inducing myocardial infarction

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Which of the following is true?

Correlation between animal study findings and outcomes of clinical trials is well established

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Farm pigs are suitable for chronic device studies

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Experimental preclinical studies for devices are used to assess deployment, safety, and functionality, as well as, efficacy to support first in man, IDE and CE Mark studies

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Practice Quiz: Large Animal Model for Heart Failure, Valvular Disease, Coronary Artery Disease, and Device Testing – Daniel Burkhoff

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Practice Quiz: Large Animal Model for Heart Failure, Valvular Disease, Coronary Artery Disease, and Device Testing – Daniel Burkhoff

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